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園丁風(fēng)采

 

張瑤

2023/02/28
姓 名 張瑤 照片
學(xué)歷/學(xué)位 研究生/博士
職稱/職務(wù) 學(xué)術(shù)教授/碩士生導(dǎo)師
聯(lián)系郵箱 shc_zhangy@ujn.edu.cn
研究方向 微生物生理與代謝調(diào)控機(jī)制;酶工程與技術(shù);食品發(fā)酵技術(shù)
社會(huì)兼職 山東省食品科學(xué)技術(shù)學(xué)會(huì)理事;山東省營(yíng)養(yǎng)學(xué)會(huì)委員
主講課程 食品微生物學(xué)、食品生物技術(shù)、食品分析與檢測(cè)
科研成果及獎(jiǎng)勵(lì)
科研成果

及獎(jiǎng)勵(lì)
1、主持項(xiàng)目
(1)國(guó)家自然科學(xué)基金青年基金,32101927,產(chǎn)脂真菌卷枝毛霉脂肪酸合成酶的底物鏈長(zhǎng)選擇及中鏈脂肪酸合成的調(diào)控機(jī)制,2022-01至2024-12,30萬(wàn)元,在研,主持
(2)山東省自然科學(xué)基金面上項(xiàng)目,ZR2020MC007,SNF1/AMPK對(duì)卷枝毛霉代謝木糖合成γ-亞麻酸的作用與調(diào)控機(jī)制研究,2021-01至2023-12,10萬(wàn)元,在研,主持
(3)山東省重點(diǎn)研發(fā)計(jì)劃項(xiàng)目,2018GSF121013,基于一步利用廢棄秸稈的卷枝毛霉生產(chǎn)功能性脂質(zhì)的產(chǎn)業(yè)化研究,2018-01至2020-12,20萬(wàn)元,已結(jié)題,主持
(4)中國(guó)博士后科學(xué)基金特別資助,2015T80735,多糖對(duì)糖尿病大鼠胰島細(xì)胞功能的保護(hù)機(jī)理研究,2015-07至2018-11,15萬(wàn)元,已結(jié)題,主持
(5)中國(guó)博士后科學(xué)基金面上資助,2017M612305,產(chǎn)脂真菌卷枝毛霉脂質(zhì)積累過(guò)程還原力產(chǎn)生途徑解析,2017-05至2018-09,5萬(wàn)元,已結(jié)題,主持
(6)中國(guó)博士后科學(xué)基金面上資助,2013M531641,洋蔥伯克霍爾德氏菌脂肪酶在大腸桿菌中的分泌表達(dá)研究,2013-05至2015-06,5萬(wàn)元,已結(jié)題,主持
(7)山東省高等學(xué)校科技計(jì)劃項(xiàng)目,J16LE20,新型脂肪酶的定向改造及高效分泌研究,2016-07至2018-12,5.5萬(wàn)元,已結(jié)題,主持
(8)淄博市校城融合項(xiàng)目,2017ZBXC169,果蔬發(fā)酵復(fù)合益生菌劑的研發(fā)及規(guī)模化制備技術(shù),2017-01至2019-12,25萬(wàn)元,已結(jié)題,主持
(9)張店區(qū)校城融合項(xiàng)目,玫瑰花復(fù)合益生保健醋的研制,2022-01至2023-12,10萬(wàn)元,在研,主持
2、論文
(1) Yao Zhang*, Yanxia Wang, Junhuan Yang, Wu Yang, Xiuwen Wang, Chen Wu, Yuanda Song*, Improved γ-linolenic acid production from cellulose in Mucor circinelloides via coexpression of cellobiohydrolase and delta-6 desaturase, Journal of Agricultural and Food Chemistry, 2022, 70, 4373-4381
(2) Yao Zhang*, Yueping Yang, Silu Zhang, Qing Liu, Wenrui Dang, Yuanda Song, Lipid accumulation and SNF1 transcriptional analysis of Mucor circinelloides on xylose under nitrogen limitation, Antonie van Leeuwenhoek, 2023, doi: 10.1007/s10482-023-01810-7
(3) Yao Zhang*, Qing Liu, Pengcheng Li, Yanxia Wang, Shaoqi Li, Meng Gao, Yuanda Song*, Enhanced lipid production by addition of malic acid in fermentation of recombinant Mucor circinelloides Mc-MT-2, Scientific Reports, 2021, 11: 12674
(4) Yao Zhang*, Yuanda Song*. Lipid accumulation by xylose metabolism engineered Mucor circinelloides strains on corn straw hydrolysate. Applied Biochemistry and Biotechnology, 2021, 193: 856-868
(5) Lu Wang, Huaiyuan Zhang, Yao Zhang*, Yuanda Song. 13C metabolic flux analysis on roles of malate transporter in lipid accumulation of Mucor circinelloides. Microbial Cell Factories, 2019, 18: 154 (*corresponding author)
(6) Yao Zhang*, Yuanda Song, Lu Wang, Qing Liu, Improvement on extracellular production of recombinant Burkholderia cepacia Lu10-1 lipase by Escherichia coli, American Journal of Biochemistry and Biotechnology, 2018, 14(2): 76~87
(7) Yao Zhang, Xiao Luan, Huaiyuan Zhang, Victoriano Garre, Yuanda Song*, Colin Ratledge, Improved gamma-linolenic acid production in Mucor circinelloides by homologous overexpressing of delta-12 and delta-6 desaturases, Microbial Cell Factories, 2017, 16: 113
(8) Yao Zhang*, Lu Wang, Yuanda Song, Heterologous expression and biochemical characterization of lipase from Burkholderia cepacia Lu10-1, American Journal of Biochemistry and Biotechnology, 2017, 13(4): 233~241
(9) Chunjiu Ren#, Yao Zhang#, Weizheng Cui, Guobing Lu, Yanwen Wang, Huiju Gao, Lu Huang, Zhimei Mu*, A polysaccharide extract of mulberry leaf ameliorates hepatic glucose metabolism and insulin signaling in rats with type 2 diabetes induced by high fat-diet and streptozotocin, International Journal of Biological Macromolecules, 2015, 72: 951-959 (#co-first authors)
(10) Yao Zhang, Chunjiu Ren, Guobing Lu, Zhimei Mu*, Weizheng Cui, Huiju Gao, Yanwen Wang, Anti-diabetic effect of mulberry leaf polysaccharide by inhibiting pancreatic islet cell apoptosis and ameliorating insulin secretory capacity in diabetic rats, International Immunopharmacology, 2014, 22: 248-257
(11) Yao Zhang, Chunjiu Ren, Guobing Lu, Weizheng Cui, Zhimei Mu*, Huiju Gao, Yanwen Wang, Purification, characterization and anti-diabetic activity of a polysaccharide from mulberry leaf, Regulatory Toxicology and Pharmacology, 2014, 70(3): 687-695
(12) Yao Zhang, Lei Wang, Jian Chen, Jing Wu*, Enhanced activity toward PET by site-directed mutagenesis of Thermobifida fusca cutinase-CBM fusion protein, Carbohydrate Polymers, 2013, 97: 124-129
(13) Yao Zhang, Sheng Chen, Jing Wu*, Jian Chen, Enzymatic surface modification of cellulose acetate fiber by cutinase-CBM (Carbohydrate-Binding Module) fusion proeins, Biocatalysis and Biotransformation, 2012, 30(2): 184-189
(14) Yao Zhang, Sheng Chen, Miao He, Jing Wu*, Jian Chen, Qiang Wang, Effects of Thermobifida fusca cutinase-carbohydrate-binding module fusion proteins on cotton bioscouring, Biotechnology and Bioprocess Engineering, 2011, 16(4): 645-653
(15) Yao Zhang, Sheng Chen, Meng Xu, Artur Cavaco-Paulo, Jing Wu*, Jian Chen*, Characterization of Thermobifida fusca cutinase-carbohydrate-binding module fusion proteins and their potential application in bioscouring, Applied and Environmental Microbiology, 2010, 76 (20): 6870-6876
(16) 王璐, 張瑤*, 楊俊換, 王艷霞, 宋元達(dá). 卷枝毛霉重組菌株Mc-MT-2培養(yǎng)條件優(yōu)化及產(chǎn)油特性. 農(nóng)業(yè)工程學(xué)報(bào), 2021, 37(8): 251-258 (通訊作者)
(17) 王璐, 王偉偉, 王艷霞, 張瑤*, 宋元達(dá). 果蔬發(fā)酵乳酸菌的篩選、鑒定及發(fā)酵性能分析. 食品科學(xué), 2020, 41(10): 166-171(通訊作者)
3、授權(quán)專利
(1)張瑤, 王艷霞, 宋元達(dá), 楊武. 一種利用纖維素高效合成γ-亞麻酸的卷枝毛霉工程菌株的構(gòu)建方法及應(yīng)用. 2022.4.22, 專利號(hào):ZL202010360500.1
(2)張瑤, 宋元達(dá), 王艷霞. 一種菌酶共酵玉米秸稈生產(chǎn)微生物油脂的方法. 2022.7.8, 專利號(hào):ZL202010451634.4
(3)Yuanda Song, Ahsanul Kabir Khan, Junhuan Yang, Yao Zhang, Wu Yang, Shaoqi Li. CONSTRUCTION OF MUCOR CIRCINELLOIDES CELL FACTORY FOR PROUCING STEARIDONIC ACID AND FERMENTATION TECHNOLOGY THEREOF. 2022.5.31, Patent No. US11345937B2
(4)吳敬, 陳晟, 張瑤, 吳丹, 陳堅(jiān), 夏澤華, 一種耐熱角質(zhì)酶-CBD融合酶及其突變體和應(yīng)用, 2013.1.30, 中國(guó), ZL201110295384.0
(5)吳敬, 陳堅(jiān), 張瑤, 陳晟, 一種耐熱角質(zhì)酶-CBD的制備及其在棉纖維精練中的應(yīng)用, 2011.4.13, 中國(guó), ZL200910033667.0
(6)吳敬, 吳丹, 張瑤, 陳堅(jiān), 陳晟, 一種重組角質(zhì)酶的發(fā)酵生產(chǎn)工藝, 2011.11.30, 中國(guó), ZL200910259651.1
4、獎(jiǎng)勵(lì)情況
(1)中國(guó)商業(yè)聯(lián)合會(huì)科學(xué)技術(shù)獎(jiǎng)一等獎(jiǎng)(第五位),2021
(2)山東理工大學(xué)優(yōu)秀碩士學(xué)位論文指導(dǎo)教師,2021
(3)山東理工大學(xué)研究生優(yōu)秀成果獎(jiǎng)指導(dǎo)教師,2019
(4)第十四屆全國(guó)多媒體課件大賽優(yōu)秀獎(jiǎng)(第四位),2014
(5)山東農(nóng)業(yè)大學(xué)科技進(jìn)步獎(jiǎng), 2009


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